Originally founded by European settlers in the colonial period, Chamberlain has a long history stretching back to the early 1700s, enduring successive waves of prosperity, disaster and conflict. Throughout the 20th century, it has seen increasing levels of superhuman activity, particularly since the so-called "mystery man" explosion of the mid-thirties. Conspiracy theorists claim that Chamberlain is a major transport hub for extraterrestrial and supernatural entities. Although dismissed as crackpots by the general community, recent events suggest they are far closer to the truth than anyone ever imagined.
By the year 2032, Chamberlain has become a sprawling maze of ruins covering most of the Eastern Seaboard. In a world devastated by environmental disasters, the city is facing imminent starvation, with 25 percent of the population effectively homeless and resources dwindling literally by the hour. Entire sections of the conurb have been cordoned off to house the "itinerants", along with the various freaks, mutants and borgz flooding in from the Suburbs. Survival rates in these "Red Zones" are extremely low due to violence, disease, and malnourishment; cannibalism is becoming rife in the ghettos and back alleys.